Esse Probiotic Serum 15ml Cartridge and Bottle

The Barrier-Strengthening, Live Probiotic Serum

Discover Esse Probiotic Serum, the world’s first live probiotic serum and a breakthrough in microbiome skincare. Its water-free formula delivers more than one billion live probiotic cells per ml, activating on contact with moisture to help rebalance the skin microbiome, strengthen the skin barrier and calm inflammation.

Clinically proven in just 28 days, this advanced anti-ageing serum improves hydration, firmness, elasticity and skin texture for a smoother, plumper and more resilient complexion.

Key Features

• Four live probiotic species – Support barrier strength, hydration and microbial balance.
• Strengthens and calms – Helps reduce inflammation and improve skin resilience.
• Clinically proven – Improves firmness, elasticity, hydration, smoothness and wrinkle depth.
• Healthy-ageing support – Ideal for ageing, sensitive or environmentally stressed skin.

Why You'll Love It

Healthy skin begins with a healthy microbiome. When the balance of beneficial bacteria on the skin is disrupted, the skin barrier becomes weaker, inflammation increases and the visible signs of ageing can accelerate.

Hero Ingredients

Live Probiotic Complex

Featuring four carefully selected live probiotic species, this breakthrough complex helps restore balance to the skin's microbiome, supporting a stronger skin barrier and healthier skin function.

Advanced Microbiome Technology

Esse's pioneering biotechnology helps encourage a diverse, balanced skin microbiome—an essential foundation for long-term skin health, resilience and healthy ageing.

Discover the science behind live probiotics. Esse Probiotic Serum works by supporting your skin's microbiome—your skin's invisible ecosystem of beneficial bacteria. If you'd like to learn why the microbiome plays such an important role in healthy ageing, barrier repair and skin resilience, read my article The Role of Prebiotics, Probiotics & Postbiotics in Skincare.